01196nM2.01200024      h001 3506868\x1e002a20241209000000.0\x1e003 20250210000000.0\x1e02
5o1492112915\x1e030 zz5dr|rz|||3|\x1e037beng\x1e050 ||||||||g|||||\x1e051 m||||||\x1e060 \x1faText
\x1fbtxt\x1e061 \x1faComputermedien\x1fbc\x1e062 \x1faOnline-Ressource\x1fbcr\x1e070 BVB\x1e076 RDA-Aufnahm
e\x1e077 \x1fc0\x1e331 Test No. 444A: In Vitro Immunotoxicity\x1e335 IL-2 Luc Assay\x1e359 Orga
nisation for Economic Co-operation and Development\x1e410 Paris\x1e412 OECD Publishing
\x1e419 \x1faParis\x1fbOECD Publishing\x1fc2023\x1e425a2023\x1e433 1 Online-Ressource (28 Seiten)\x1e
435 21 x 29.7cm\x1e451 OECD Guidelines for the Testing of Chemicals, Section 4\x1e540a
ISBN 978-92-64-93474-0\x1e655e\x1fxVerlag\x1fzkostenfrei\x1f3Volltext\x1fuhttps://doi.org/10.17
87/27b10ba3-en\x1e750 This Test Guideline (TG) describes the IL-2 Luc Assay test me
thod to evaluate the potential immunotoxic effects of chemicals on T lymphoblast
ic cell line. This cell line allows quantitative measurement of luciferase gene 
induction by detecting luminescence from well-established light producing lucife
rase substrates as indicators of the activity of IL-2, IFN-\\u03b3 and GAPDH in c
ells following exposure to immunotoxic chemicals. The method is intended to be u
sed as a part of a battery to determine immunotoxic potential of chemicals\x1e\x1d